A highly enantioselective approach towards 2-substituted 3-bromopyrrolidines.
نویسندگان
چکیده
A facile and highly enantioselective approach towards 2-substituted 3-bromopyrrolidines has been developed. The process involves an amino-thiocarbamate catalyzed bromoaminocyclization of 1,2-disubstituted olefinic amides. The pyrrolidine products could readily be converted into other useful building blocks including a dihydropyrrole and a 2-substituted pyrrolidine.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 19 شماره
صفحات -
تاریخ انتشار 2012